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KMID : 0608520060120010091
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Korean Journal of Oriental Medicine
2006 Volume.12 No. 1 p.91 ~ p.102
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Protective Effect of Kun YangDan on Motility and Viability of Sperms Exposed by Diethylhexyl Phthalate
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Ma Jin-Yeul
Nam Chang-Uk
Park Kyoung-Soo
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Abstract
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We treated KunYangOan (KYD) in SD rats in order to examine the protective effect against cell damage induced by diethylhexyl phthalate (DEHP). KYD reduced DEHP toxicity by increasing the function of immune cell numbers, weight increase of spleen, red blood cells, HB, and HCT content, sperm number and mobility, resulting in improving reproductive function by judging from the recovery of testosterone content. Interestingly, the hormone change of testosterone by KYD significantly recovered the decreased its level. Taken together, these results suggest that KYD specifically affect the reproductive function induced by DEHP, an endocrine disruptor.
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KEYWORD
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Protection, Sperms, Phthalate, KunYangDan
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